Comparison to Classic column based synthesizers

Kilobaser: the smart cartridge based DNA synthesizer

Kilobaser is designed as a personal DNA synthesizer to fulfill the needs of individual scientists or small labs. Due to its reagents cartridge technology & full automation it is extremely simple to use and doesn’t require especially trained people. Additionally, its low price point, yield of 300 pmol and the single column microfluidic chips makes Kilobaser the perfect choice for scientists to accelerate their research.

Overview

Kilobaser Classic column based synthesizers
Acquisition costs
Control
Reagent consumption / waste
Infrastructure
Automation / hands-on time
Oligo modification flexibility
Parallel columns
User friendliness

Details

  • kilobaser
    • 15.000 € / 18.000 USD
      • Local touchscreen and remote control
      • 5mL for 100 bases DNA
      • Basic ventilation
      • automatic final deprotection
      • Oligo modification flexibility:
        limited modifications
      • Parallel columns:
        single column
      • reagent cartridge
      • 300 pMol
    • request sample oligo
  • Classic column based synthesizers
    • > 35 000 € / 40 000 USD
      • External computer needed
      • 50 - 100 x more
      • Fume hood / exhaust needed
      • manual final deprotection
      • Oligo modification flexibility:
        any modification
      • Parallel columns:
        2 - ? columns
      • > 10 reagent bottles
      • >10 nMol

In contrast the classic DNA synthesizer available on the market are rather production machines, suffering from a high price point, complex operation and high reagent consumption, but offering more flexibility and maximum output in terms of yield, parallel columns, high customizability. These classic DNA synthesizers are usually operated by synthesis service providers or seperate synthesis departments in larger organisations.

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